Harvard Medical School and its affiliated hospitals contain a vibrant set of world-class labs working in epigenetics and gene expression. Research ranges from studies of fundamental mechanisms of gene regulation, to development of small molecule inhibitors of transcription and epigenetic regulators, to investigations of human disease. The mission of the HMS Epigenetics & Gene Dynamics Initiative is to provide support, resources, and interactions for our community, in order to accelerate scientific discoveries in this exciting domain.
Defects in gene expression and chromatin structure underlie a great number of developmental disorders and diseases, including cancer, immune and neuronal dysfunction, and metabolic syndromes. By facilitating collaboration and sharing of knowledge between Harvard-affiliated labs and hospitals, we aim to leverage our strengths to deepen our understanding, innovate novel technologies, and develop new therapeutic strategies.
- Support research. We provide funding for collaborative projects and student/postdoc travel grants. Please note that at this time we have paused all funding opportunities until further notice. (Updated: July 2020)
- Develop and disseminate novel technologies. We have recently established the Nascent Transcriptomics Core, a resource for monitoring RNA synthesis and processing, and for the analysis of this data. Interested in using nascent RNA to directly identify gene expression changes, active enhancers, and non-coding RNA loci? Click here for more information on the Nascent Transcriptomics Core
- Provide many types of opportunities for interactions and information sharing across the Harvard Medical School community. Learn More.